Psychopharmacology
Recent articles
- Reduced cortical GABA and glutamate in high schizotypyAbstract Rationale Abnormal functioning of the inhibitory gamma-aminobutyric acid (GABA) and excitatory (glutamate) systems is proposed to play a role in the development of schizophrenia spectrum disorder. Although results are… Read more »
- Geniposide ameliorates chronic unpredictable mild stress induced depression-like behavior through inhibition of ceramide-PP2A signaling via the PI3K/Akt/GSK3β axisAbstract Background Depression is a severe mental disorder. Unfortunately, more than half of patients with major depression disorder cannot achieve remission after initial treatment with an antidepressant. Geniposide, a bioactive… Read more »
- Acute drug effects differentially predict desire to take dextroamphetamine again for work and recreationAbstract Rationale Misuse of dextroamphetamine occurs in work and recreational contexts. While acute drug effects broadly predict abuse liability, few studies have considered the relationship between acute effects and context.… Read more »
- Correction to: Sign‑ and goal‑tracking score does not correlate with addiction‑like behavior following prolonged cocaine self‑administrationA Correction to this paper has been published: https://doi.org/10.1007/s00213-021-05891-y Read more »
- Sex differences in specific aspects of two animal tests of anxiety-like behaviorAbstract Rationale Anxiety, a negative state of high arousal and vigilance, is especially prevalent in women, making identification of underlying mechanisms critical for developing effective therapies. With the challenge of… Read more »
- Comments on “Sigma-1 receptor ligands improves ventricular repolarization-related ion remodeling in rats with major depression disorder”Abstract With respect to Guo’s inspiring article (Guo et al. 2021), we would like to suggest several corrections about some of the figures. We felt obliged to write this erratum… Read more »
- Adaptive aspects of impulsivity and interactions with effects of catecholaminergic agents in the 5-choice serial reaction time task: implications for ADHDAbstract Background Work in humans has shown that impulsivity can be advantageous in certain settings. However, evidence for so-called functional impulsivity is lacking in experimental animals. Aims This study investigated… Read more »
- Emotion recognition in individuals with cocaine use disorder: the role of abstinence length and the social brain networkAbstract Rationale Emotion recognition is impaired in drug addiction. However, research examining the effects of cocaine use on emotion recognition yield mixed evidence with contradictory results potentially reflecting varying abstinence… Read more »
- Haloperidol rescues the schizophrenia-like phenotype in adulthood after rotenone administration in neonatal ratsAbstract Neuropsychiatric disorders are multifactorial disturbances that encompass several hypotheses, including changes in neurodevelopment. It is known that brain development disturbances during early life can predict psychosis in adulthood. As… Read more »
- The DRD2 Taq1A polymorphism moderates the effect of PTSD symptom severity on the left hippocampal CA3 volume: a pilot studyAbstract Rationale and objectives The hippocampus, especially the CA1, CA3, and dentate gyrus (DG) subfields, is reported to be associated with post-traumatic stress disorder (PTSD) after trauma. However, neuroimaging studies… Read more »
- Inhibition of protease-activated receptor 1 (PAR1) ameliorates cognitive performance and synaptic plasticity impairments in animal model of Alzheimer’s diseasesAbstract Introduction Alzheimer’s disease (AD) is a progressive brain disorder accompanied with synaptic failures and decline in cognitive and learning processes. Protease-activated receptor 1 (PAR1) is the major thrombin receptor… Read more »
- The effects of voluntary adolescent alcohol consumption on alcohol taste reactivity in Long Evans ratsAbstract Rationale The relationship between age, ethanol intake, and the hedonic value of ethanol is key to understanding the motivation to consume ethanol. Objective It is uncertain whether ethanol drinking… Read more »
- Effects of GABAA receptors in nucleus cuneiformis on the cannabinoid antinociception using the formalin testAbstract Rationale Nucleus cuneiformis (NC), a reticular nucleus of the midbrain, is a part of the descending pain modulatory system and therefore has an important role in pain perception. Objectives… Read more »
- Mechanism and therapeutic strategies of depression after myocardial infarctionAbstract Depression resulted as an important factor associated with the myocardial infarction (MI) prognosis. Patients with MI also have a higher risk for developing depression. Although the issue of depression… Read more »