Psychopharmacology
Recent articles
- Sex differences in affective states and association with voluntary ethanol intake in Sprague–Dawley ratsAbstract Alcohol use disorders (AUDs) are a major problem across the USA. While AUD remains a complex human condition, it is difficult to isolate the directionality of anxiety and ethanol… Read more »
- Acute pain-related depression of operant responding maintained by social interaction or food in male and female ratsAbstract Rationale Clinically relevant pain is often associated with functional impairment and behavioral depression, including depression of social behavior. Moreover, recovery of function is a major goal in pain treatment. We… Read more »
- Analysis of recreational psychedelic substance use experiences classified by substanceAbstract Rationale and objectives Differences among psychedelic substances regarding their subjective experiences are clinically and scientifically interesting. Quantitative linguistic analysis is a powerful tool to examine such differences. This study… Read more »
- Effects of cannabidiol on symptoms induced by the recall of traumatic events in patients with posttraumatic stress disorderAbstract Studies with cannabidiol (CBD) suggest that this compound has anxiolytic properties and may mediate the reconsolidation and extinction of aversive memories. The objective of this study was to test… Read more »
- Assessing the risk–benefit profile of classical psychedelics: a clinical review of second-wave psychedelic researchAbstract Rationale A broad reassessment of the potential benefits of psychedelic drugs has led to the initiation of multiple major clinical trials in an effort to advance their status to… Read more »
- Effects of episodic future thinking on reinforcement pathology during smoking cessation treatment among individuals with substance use disordersAbstract Rationale Reinforcer pathology (RP) is a theoretical model based on two processes: delay discounting (DD) and drug demand. Given that RP has been shown to have a predictive value… Read more »
- Prevalence and self-reported reasons of cannabis use for medical purposes in USA and CanadaAbstract Rationale There has been increasing attention on cannabis use for medical purposes, but there is currently a lack of data on its epidemiology. Objectives To examine the epidemiology of… Read more »
- On the interrelation between alcohol addiction–like behaviors in ratsAbstract Rationale Alcohol use disorder (AUD) is a complex, heterogeneous disorder that only occurs in a minority of alcohol users. Various behavioral constructs, including excessive intake, habit formation, motivation for… Read more »
- Peer presence and familiarity as key factors to reduce cocaine intake in both rats and humans: an effect mediated by the subthalamic nucleusAbstract Rationale Stimulant use, including cocaine, often occurs in a social context whose influence is important to understand to decrease intake and reduce associated harms. Although the importance of social… Read more »
- Caffeine and attentional control: improved and impaired performance in healthy older adults and Parkinson’s disease according to task demandsAbstract Introduction Caffeine is frequently consumed to boost goal-directed attention. These procognitive effects may occur due to the adenosine-mediated enhancement of monoamines, such as dopamine, after caffeine administration. As such,… Read more »
- Rrn3 gene knockout affects ethanol-induced locomotion in adult heterozygous zebrafishAbstract Genome-wide analysis has identified the transcription factor, RRN3 (or TIF-1A), on human chromosome 16p13.11 as a candidate gene associated with mental disorders. Both genetic and biochemical experiments have demonstrated… Read more »
- Early social isolation stress increases addiction vulnerability to heroin and alters c-Fos expression in the mesocorticolimbic systemAbstract Rationale Adverse psychosocial factors during early childhood or adolescence compromise neural structure and brain function, inducing susceptibility for many psychiatric disorders such as substance use disorder. Nevertheless, the mechanisms… Read more »
- Cannabidiol inhibits methamphetamine-induced dopamine release via modulation of the DRD1-MeCP2-BDNF-TrkB signaling pathwayAbstract Rationale Adaptive alteration of dopamine (DA) system in mesocorticolimbic circuits is an extremely intricate and dynamic process, which contributes to maintaining methamphetamine (METH)-related disorders. There are no approved pharmacotherapies… Read more »